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Chem Biol Interact 103:79129 Visanji JM, Duthie SJ, Pirie L et al (2004) Dietary isothiocyanates inhibit Caco-2 cell proliferation and induce G2/M phase cell cycle arrest, DNA damage, and G2/M checkpoint activation

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In keeping with this observation, here we unveil a crucial role of GSH in lipid production, as the synthesis of GSH, specifically in the liver, is required for sustaining physiological circulating triglyceride levels (an important energy source) and adipose tissue homeostasis under standard dietary regimen

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Apart from these modes of action, riboflavin has also been shown to activate specific neuroactive molecules such as vitamin B 6 (which confers neuroprotection based on a role in serotonin production) 73 , homocysteine (which has a double-edged neurological role) 74 and kynurenine involved in glutamate excitotoxicity (i.e., excess of glutamate in neural synapse, resulting in death of neural cells) 75

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