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A 2025 meta-analysis of 16 studies involving 6,098 participants found no statistically significant difference between intramuscular, oral, and sublingual B12 supplementation routes (p=0.270)

This removes any ambiguity about when the medication needs to be replaced

It can become tricky to ensure that your diet contains enough of all of the necessary vitamins to maintain the health of your body

It is also commonly added to various foods and beverages as a nutritional supplement

When to See Your Care Team Book a 1:1 consultation with a licensed care team lead if B12 is below 300 pg/mL with any neurological symptoms (tingling, balance problems, memory issues), or if B12 is below 200 pg/mL regardless of symptoms