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Medicine has learned hard lessons from past cure-alls that went awry

The primary endpoint of the study was the number of treatment-related adverse events from baseline to the end of follow-up at 26 weeks, while the exploratory endpoints were changes in body weight, glycemic parameters, and various hormones

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Peer-reviewed clinical trial data published in the New England Journal of Medicine establishing semaglutides efficacy for chronic weight management, with average weight loss of 14.9 percent of body weight at 68 weeks positions these as a fundamentally different category of intervention than peptides like GHK-Cu