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However, during inflammatory reactions, exposure of macrophages to interferon (IFN) and TNF results in the activation of the inducible isoenzyme of NOS (iNOS), which increases up to 10 times the levels of nitric oxide

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J Nutr Biochem 25:456462 [DOI] [PubMed] [Google Scholar] Polat N, Ciftci O, Cetin A, Ylmaz T (2016) Toxic effects of systemic cisplatin on rat eyes and the protective effect of hesperidin against this toxicity