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APIs of Sirt1 at H3K18 were 1.58, 1.69, and 2.32 in three independent experiments, which means that Sirt1 prefers deacetylation compared to debutyrylation at this site

Curiously, when treated with injectable B12, the affected babies can develop a peculiar transient "batwing dystonia" that may represent a "nutritional recovery" movement disorder (135)