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Safety signals remain in a black bo: no reports have been made regarding the effects of high-dose intravenous Vit C on renal function, long-term NOX-ASO on neutrophil function, or nanoenzyme mucosal deposition kinetics

Gan To Kagaku Ryoho 9:14741481 Dai X, Stanilka JM, Rowe CA, Esteves EA, Nieves Jr C, Spaiser SJ, Christman MC, Langkamp-Henken B, Percival SS (2015) Consuming Lentinula edodes (Shiitake) mushrooms daily improves human immunity: a randomized dietary intervention in healthy young adults

The rodent studies typically use dosages equivalent to roughly 110 mcg/kg of body weight when allometrically scaled to humans, which puts a 200 lb person right in that 200500 mcg sweet spot

TB4-Frag Max provides a higher potency formulation with additional ingredients designed to enhance absorption and activity