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Front Immunol (2018) 9:1206

But chronic psychological stress does elevate cortisol levels, which can impair ovarian blood flow, disrupt hormonal signalling, and increase systemic oxidative stress, all of which may affect the follicular environment. While acute stress is unlikely to damage egg quality, prolonged or severe stress may compound the effects of other risk factors

Recent advances in nanotechnology have yielded multifunctional platforms incorporating GSH-responsive linkages, redox-active metals, and prodrug designs with strong promise for targeted delivery and theranostics

The most important pathway involves glutathione peroxidase (GPx) and glutathione reductase (GR)

McKee reports support for attending meetings and/or travel from Population Health Research Institute, McMaster University