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deficiency can cause harm to fetus (neurodevelopment issues)

In addition, berberine treatment was found to significantly increase IL-10 levels (Kim et al., 2015)

In this type of signalling, cascades chiefly comprise the activation or deactivation of MAPPKKS (MAP3Ks), MAPKKs (MAP2Ks), and MAPKs, which themselves consecutively phosphorylate a wide array of target proteins and transcription factors [103] (Fig