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Disruption of xCT inhibits cell growth via the ROS/autophagy pathway in hepatocellular carcinoma

Genetic polymorphisms of alcohol and aldehyde dehydrogenases and glutathione S -transferase M1 and drinking, smoking, and diet in Japanese men with esophageal squamous cell carcinoma, Carcinogenesis , Volume 23, Issue 11, November 2002, Pages 18511859, For answers or to make an appointment, call us toll-free at 800-923-7878 to speak with a Patient Care Team

Wei J, Yu X, Yang L, Liu X, Gao B, Huang B, Dou X, Liu J, Zou Z, Cui XL, Zhang LS, Zhao X, Liu Q, He PC, Sepich-Poore C, Zhong N, Liu W, Li Y, Kou X, Zhao Y, Wu Y, Cheng X, Chen C, An Y, Dong X, Wang H, Shu Q, Hao Z, Duan T, He YY, Li X, Gao S, Gao Y, He C

Interestingly, N-acetylcysteine (NAC) which readily enters cells to convert to cysteine for GSH generation, is an important antioxidant 13

doi: 10.1038/s41467-021-26310-y