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Endothelial Dysfunction, inflammation and coronary artery disease: potential biomarkers and promising therapeutical approaches

Temporal scaling of lifespan is not evident when ferroptosis is inhibited, consistent with this cell death process acting at specific life phases to induce organismal frailty, rather than contributing to a constant aging rate

Youngblood et al., 2020

Early-phase trials of liposomal (Lipocurc) and polymeric (NanoCurc) curcumin demonstrate target engagement and biological activity but underscore persistent bioavailability challenges and dose-limiting toxicities (e.g., hemolysis at 300 mg/m)