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Role for drug transporters in chemotherapy-induced peripheral neuropathy

115 This finding reinforces the role of DNA methylation profiling in optimizing treatment regimens

Furthermore, a reduction in cortical parvalbumin-positive interneurons, a hallmark of SZ, can also be triggered by NMDAR antagonists 14 , suggesting that they may be particularly vulnerable to NMDAR hypofunction (the relatively young age of the rats used in the current study prevented analysis of parvalbumin-positive interneurons since they are yet to develop)