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Oral administration of levodopa depends on adequate GI function, yet the drug has been shown to delay gastric emptying in healthy individuals and to aggravate GI symptoms in patients with PD [88]

HUVECs Human umbilical vein endothelial cells

Brain 131 , 17491758 (2008)

Lipid peroxidation, a principal feature of ferroptosis, generates products such as MDA, 4-hydroxyhexenal, and 4-HNE that serve as valuable indicators for assessing the extent of lipid peroxidation and ferroptosis (14, 56)

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