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It promotes neutrophil chemotaxis and degranulation leading to local inflammation in damaged tissues 37

Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1

Gynecomastia is a condition where male breast tissue becomes enlarged, causing the chest to appear fuller or more feminine

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Detectable CNS concentrations have been observed within minutes, suggesting a potentially faster onset than peripheral administration under specific experimental conditions (Hanson and Frey, 2008) (Figure 4C)