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* Correspondence: Valeria Calcaterra, [email protected] These authors have contributed equally to this work and share first authorship These authors have contributed equally to this work and share last authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Supplemental doses of vitamin A greater than 10,000 IU (3,000 mcg retinol activity equivalents [RAE]) have been found to be dangerous during the first trimester of pregnancy