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2016) underscoring their potential as powerful therapeutic agents in overcoming cancer treatment resistance

Neurological examination revealed tetraparesis, with paraesthesia of the extremities

The established electrostatic interactions between residues Glu1581 and Gln1355 in the FAT domain and between residues Arg1585 of the FAT domain and Glu2311 of the C-lobe in the fully active state indicate direct communication between the FAT domain and the kinase domain to promote the active state (Fig

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