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found that DHA triggered ferroptosis to eliminate the activation of HSC, which characterized by iron overload, GSH depletion, lipid ROS accumulation, and peroxidation, whereas Fer-1 and Lip-1 inhibited the DHA effect (93)

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Demirev PA, Hagan NS, Antoine MD, Lin JS, Feldman AB

It is still undefined whether the blocking of one TF does not influence the others and how much the blocking of OLIG2 during the maturation of the CNS can affect its correct development

Characterizing the CF oxidative stress proteome remains essential for identifying therapeutic targets and evaluating treatment efficacy