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Diabetic polyneuropathy in type 2 diabetes mellitus: inflammation, oxidative stress, and mitochondrial function

and transformation of muscle fibers from type I (slow twitch) to type II (fast twitch), particularly type IIB, which possess less oxidative capacity than type IIA or type I fibers

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And they point the way to a new class of antidepressants that could be freer of side effects and faster-acting than those in use today, and that may help patients for whom existing treatments don't work or have stopped working