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In experiments with primary patient-derived cells, responses were measured after 3 days of incubation

3f), suggesting that carbon flux to 2-OG is a rate-limiting step for glutamate production, which may be increased by the expression of CgCS and/or CitS

[DOI] [PubMed] [Google Scholar] 91.Brufani M., Figliola R

Vion AC, Perovic T, Petit C, Hollfinger I, Bartels-Klein E, Frampton E, Gordon E, Claesson-Welsh L, Gerhardt H (2021) Endothelial cell orientation and polarity are controlled by shear stress and VEGF through distinct signaling pathways