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Thats why results are gradual and systemic

Insulin regulates glucose concentration in the plasma and also causes potassium to move into cells until the kidneys have sufficient time to excrete the dietary potassium load and re-establish total-body potassium content

Wang M, Liu L, Li H, Li Y, Liu H, Hou C, Zeng Q, Li P, Zhao Q, Dong L, Zhou G, Yu X, Liu L, Guan Q, Zhang S, Wang A (2020) Thyroid function, intelligence, and low-moderate fluoride exposure among Chinese school-age children

Co-stimulation A ligandreceptor signal provided by activated antigen-presenting cells (for example, B7-1 on antigen-presenting cells engaging CD28 on T cells) that leads to full T cell activation

(3) heat shock protein 1 (HSPBL), which protects cells from lipid ROS (30)