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8,9 In late stages cord atrophy in thoracic region is the only finding seen

In fact, a retrospective study has shown that higher expression of CD38 on tumor-infiltrating plasma cells correlates with increased disease-free survival and overall survival [49]

The amplification of the embedded labeling provides a signal identified by a laser (Illumina iScan System), which excites the fluorophores at each base, allowing for the identification of methylated sites in the studied DNA