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revealed that endogenous adenine plays a role in the progression of renal disease in DKD patients by activating the mTOR pathway, which is crucial for cellular energetics pathways [56]

Ind J Crit Care Med

Similarly, common comorbidities such as sinusitis, rhinitis, asthma and gastro-oesophageal reflux disease may exacerbate symptoms and may need independent treatment at the time of exacerbation