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When a healthy body encounters a severe viral pathogen like SARS-CoV-2, it mounts a massive immune response

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Second, the doses are small because the target is a high-affinity intracellular enzyme, not a receptor that needs saturating with milligrams of drug

Current studies predominantly target cell-based or peptide-based vaccines, while viral-based and nucleic acid-based options remain less explored, likely due to their emerging status