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794,795 Moreover, since the elucidation of the crystal structure of FTO in 2010, a range of inhibitors targeting its substrate binding sites has been developed, including anthraquinone, entacapone, meclofenamic acid (MA), MA2, as well as FB23 and FB23-2

Studies have demonstrated that GA could ameliorate hypertension through multiple mechanisms, including reducing systolic blood pressure, decreasing the thickness and weight of the aortic wall, and mitigating cardiac fibrosis (Jin et al., 2017a

The terpenes found in COs were beta-myrcene, d-limonene, terpinolene, linalool, beta-caryophyllene, alpha-humulene, (-)-guaiol, (-)-alpha-bisabolol