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Description

However, in order to enhance the capabilities of the GSH-modified GNPs, additional modification strategies are needed

Valosin-containing protein phosphorylation at Ser784 in response to DNA damage

Limitations : Invasive with risks (e.g., hypoparathyroidism, recurrent laryngeal nerve damage), necessitates lifelong thyroid hormone replacement therapy

This design offers additional benefits, such as the ability for NPs to accumulate in diseased tissues and be protected and released in a targeted manner by MPs