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69 Metabolic reprogramming One hallmark of tumors is altered energy metabolism, with the most well-known example being the Warburg effect

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Observing this dynamic pattern supports the presence of an epileptic seizure, whereas the absence of any changes in pupillometry might suggest a pseudoseizure

Molinari C, Uberti F, Grossini E, Vacca G, Carda S, Invernizzi M, Cisari C

Similarly, targeting molecular chaperone complexes with small molecule modulators (e.g., 17-AAG, YM-1) has been shown to reduce neurotoxicity and enhance receptor-dependent degradation (reviewed in 81)