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Proinflammatory cytochromes such as TNF-, IL-6, and IL-1 are also inhibited to significantly reduce NO levels (53)

Multiple metabolic pathways associated with glutamine, such as glutamine-mTOR signaling, glutamine-glutamate-other amino acid pathway, glutamine-ISR stress pathway, and glutamine-autophagy pathway, have been observed to modulate the differentiation of Th17 and Tregs [136]