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10.1016/j.freeradbiomed.2018.03.007 117 YoonS

The DNA sequencing data from patients and PDXs used in this study has been deposited in the European Genome-Phenome Archive under accession code EGAS00001006494

Reina Yokoyama Birthday: February 22nd 2001, 15 years old From: Saitama Height: 152.5cm Hobbies: Singing and dancing Special skill: Alto saxophone and jazz dance Became a member of Hello!Project Kenshuusei in September 2016 Kaede Kaga Birthday: November 30th 1999, 17 years old From: Tokyo Height: 162cm Hobbies: Karaoke, anime Special skills: Trumpet and Kendo Became a member of Hello!Project Kenshuusei in November 2011

Conclusion The discovery of cuproptosis offers a novel approach for cancer therapy by exploiting the pathophysiological role of copper

Although the genetic ablation of CNDP2 does not cause a vast change in Cys-Gly dipeptidase activity, APAP overdose induces renal damage more severely than that encountered in wild-type mice