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The NO-deficient mutant nos1/noa1 showed early leaf senescence ( Arabidopsis expressing an NO degrading dioxygenase (NOD) displayed a senescence-like phenotype ( Figure 2 )

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And last year, despite not having a Covid vaccine or therapy in its armor, it moved up to the number four slot, just behind Johnson & Johnson, Pfizer and Roche, with a turnover of US$ 56.2 billion