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Moreover, a possible decrease in CPT-I activity and reduced -oxidationboth of which may contribute to an underlying energy deficit in the study patientsprompted us to assess plasma triglyceride (TG) levels to further explore lipid metabolic disturbances

But this is a more serious problem in the brain because the brain is much more fragile than other organs and does not have as much room to expand and swell

Neurons from differentiated groups were stained with MitoTracker Deep Red (200 ng/ml) (Yeasen, Shanghai, China) for mitochondria for 60 min, then fixed with 4% paraformaldehyde for 15 min and permeabilised with Triton X-100 at 0.04% as previously described in ref

Biomed pharmacother = Biomed pharmacotherapie (2023) 162:114606

This raises concerns about generalizability across disease etiologies and stages