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These results demonstrate that inhibiting ferroptosis, rather than activating the AMPK pathway, is the primary mechanism of action of metformin against IIRI

10.1038/s41388-018-0243-y 17 BogaczM.Krauth-SiegelR

Rather, patients with diabetes taking metformin should only do so if instructed by their physician, as they can help you further determine the proper dosage amount, as well as what form of supplementation would be best