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Chromatin-bound MDM2 regulates serine metabolism and redox homeostasis independently of p53

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Sci Adv 7: eabg3750

Hence, we suggest that NACs anti-relapse effect is mediated through modulation of the glutamatergic system, enhancing extinction learning specifically via activation of mGluR 2/3 receptors

Based on current study findings, DOX-induced acute nephrotoxicity may be prevented by administration of ORES and/or DAPA through changes to the PPAR-/Nrf-2/HO-1, NF-B/TNF-/Keap-1, and Bcl-2/Caspase-3/ATG-5 pathways