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At the same time, approximately one-third of patients had complete necrosis on the explant

10.3390/nu15020291 Nutrients

Oppitz SJ, Garcia MV, Bruno RS, et al

Constant exposure to sunlight, pollution, dust, humidity, stress, and unhealthy lifestyle habits often leads to pigmentation, tanning, dullness, uneven skin tone, acne marks, and premature signs of aging