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p53: protection against tumor growth beyond effects on cell cycle and apoptosis

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L.WeaverE

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(ii) a rise in the levels of putrescine, a derivative metabolite from arginine (urea cycle), and the chemokine CCL2 leading to M2 macrophages differentiation and the impairment of antitumor immunity

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Firstly, to quantify the glycolytic activity of ILC2s ex-vivo, we analyzed their production of L-lactate, a terminal metabolite produced in the glycolysis pathway, noting that melatonin treatment precipitated a marked decrease in concentration ( Figure 5G )

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