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About this article Cite this article Talebi, S.S., Ghasemi, M., Etminani-Esfahani, M

T cell development in mice lacking all T cell receptor family members (,, and FcRI)

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This upregulation occurs under hypoxic conditions, leading to its binding to HIF-1 within the cell nucleus, where HIF-1 interacts with hypoxia response elements (HREs) to induce the activation of numerous downstream genes (104)