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*Correspondence: Yan Yuan, [email protected] This article was submitted to Virology, a section of the journal Frontiers in Microbiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Several underlying mechanisms, including alteration of the gut microbiome, modulation of intestinal barrier function and immune response, reduction in the level of endotoxins, and bacterial translocation, have been implicated through which probiotics can effectively suppress the occurrence of alcohol-induced liver disorders

FIGURE 2 Astrocytic activation was assessed in the M1 region of the brain at 130 days by the immunohistochemistry staining of GFAP