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Although oral semaglutide might be a better option for patients who are allergic to injections or reluctant to self-inject, its efficacy may be limited by its stringent administration guidelines, which call for taking it half an hour before the first meal, drink, or other medication [90]

Laboratory monitoring in known users should include IGF-1, fasting insulin, lipid profile, and careful dermatological surveillance

Digestive effects seem rare with injectable administration but occasionally reported

Whats more, as we have seen above, CFS is a chronic condition that persists over time