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9 Where IF is present, a deficiency can easily be overcome by oral supplementation of crystalline cobalamin, which does not need to be cleaved from food proteins

For patients who do not respond to first-line therapy, such as oral medications, ICP, or penile injection therapy, is a powerful alternative

142 In a placebo-controlled trial in 60 men with low sperm motility and increased DNA fragmentation, 400 IU vitamin E plus 200 mcg selenium for three months improved sperm motility and viability

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10 Impaired methylation due to insufficient B12 can reduce the efficiency of neuronal maintenance, synaptic function, and myelination