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When this vitamin is deficient, the transmission of nerve impulses is impaired

Mediation of metabolism USP21 USP21 has been established as a mediator of Forkhead box D1 (FOXD1) ubiquitination reversal

At high extracellular concentrations, glutamate causes neuronal damage by promoting oxidative stress which can lead to cellular death

GSH probably engages a partnership with Grx3 and Grx4, with which it forms in vitro unusual FeSbridged dimeric complexes that are coordinated by its Cys residue and the glutaredoxin active site ones (Li et al , 2009