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This distinction has important clinical implications, as defining a pathogenic role of increased VEGFA signaling in specific aging diseases may suggest novel therapeutic approaches for these diseases that target VEGFA pathway hyperactivation or downstream cellular pathomechanisms that occur as a consequence of increased VEGFA levels

Ortenberg R, Gon S, Porat A, Beckwith J

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Aging-associated accumulation of mitochondrial DNA mutations in tumor origin

Gpx1 modulates Con A-induced CD4+ T cell in the spleen In Con A-induced hepatic injury, T cells can be classified into two groups such as exogenous and endogenous