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This could indicate that these GSTs are involved in early responses to oxidative stress

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2.7 Statistical analysis Data are shown as mean values SEM of n = 4 independent experiments per group, each in duplicate

12 As a consequence, dehydration of the nucleus pulposus (NP) occurs with subsequent reduction of disc height and shock-absorbing capacity, thus leading to transmission of circumferential forces to the annulus fibrosus (AF) eventually resulting in AF tears which predispose to discogenic LBP, herniations and further degenerative changes

Kumar A, Connelly K, Vora K, Bainey KR, Howarth A, Leipsic J, Betteridge-LeBlanc S, Prato FS, Leong-Poi H, Main A, Atoui R, Saw J, Larose E, Graham MM, Ruel M, Dharmakumar R (2024) The Canadian Cardiovascular Society classification of acute atherothrombotic myocardial infarction based on stages of tissue injury severity: an expert consensus statement