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Importantly, in addition to the N-terminal cytosolic tail of GNPT interacting with COPI, the cytosolic tails of LYSET associate with the COPI adaptor GOLPH3 and retromer to maintain the LYSET-GNPT complex at the Golgi

During this time, 12 (4.4 percent) men in the testosterone group died, while in the untreated control group, 57 deaths (30.2 percent) , 47 myocardial infarctions (24.9 percent) and 44 strokes (23.3 percent) occurred