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Novel curcumin-loaded gel-core hyaluosomes with promising burn-wound healing potential: development, in-vitro appraisal and in-vivo studies

4.3.2 Hypoxia GB TME features a necrotic core primarily formed due to high cell density or vaso-occlusive events leading to hypoxia, a pervasive feature in GB

In this review, we briefly cite some studies related to opioid receptors concerning NP to highlight the role of opioid receptors and to explain the poor therapeutic effect of opioids

Recent studies have pointed to disruptions in various metabolic pathways involved in seizure initiation, propagation, and resistance to ASMs 7,8

Overall, the combination of artemisinin with different chemotherapy agents and other natural compounds demonstrates significant anti-tumor effects, including enhancing the anti-proliferation, pro-apoptotic, and cell cycle regulation effects of oxaliplatin, metformin, and carboplatin on various cancer cell lines