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This metabolic pathway yields the one-carbon unit necessary for the formation of the methyl donor SAM through processes mediated by serine hydroxymethyltransferase 2 (SHMT2) [75]

M., Montenegro, F

This is achieved through optimized fabrication techniques like emulsion-solvent evaporation, yielding particles with sizes around 145 nm, a zeta potential of approximately 21.8 mV, and encapsulation efficiencies reaching 94% in optimized formulations, while maintaining colloidal stability for at least 1 month under physiological conditions [97]

PMID 19052378

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