Deficiency in CSE promotes neurodegeneration in Huntingtons disease [18], whereas deficiency in ethylmalonic encephalopathy 1 (ETHE1 or persulfide dioxygenase, PDO), a H 2 S catabolizing enzyme, is a cause of ethylmalonic encephalopathy, which is characterized by abnormally high H 2 S levels in tissues and blood [19]
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An Fc variant with two mutations confers prolonged serum half-life and enhanced effector functions on IgG antibodies
