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Mulvey et al., 2014

Nov 3 2016;16(1):137

S-nitrosylation of cyclin-dependent kinase 5 (cdk5) regulates its kinase activity and dendrite growth during neuronal development

In the present study, we seek to investigate the protective effect of various endogenous metabolites of 17-estradiol (E 2 ) and estrone (E 1 ) against oxidative neurotoxicity using both in vitro and in vivo models, and also to determine the mechanism underlying their neuroprotective action