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The mechanism of action of this compound involves the promotion of apoptosis by increasing the production of ROS in two types of GBM cells

The indirect inhibition of P-gp and MRP2- mediated efflux by gatifloxacin is through ATP inhibition and fluoroquinolones were proven not to be substrates of BCRP

The specific mechanism underlying the increase in mortality may be associated with the regulation of biofilm formation, biofilm dispersion, hyphae growth, and antifungal sensitivity of C

J Exp Bot 67:38313844 Miller GAD, Suzuki N, CiftciYilmaz SULTAN, Mittler RON (2010) Reactive oxygen species homeostasis and signalling during drought and salinity stresses