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The systematic review also reported trivial effect on erectile function compared to a placebo and with little to no side effects

Dyken and Lacoste 2018)

GPX4 deletion led to neuronal death in the hippocampal area of neonatal and adult mice, along with increased astrocyte activation, indicating that GPX4 serves as a defensive sentinel during nervous-system degeneration processes (Yoo et al., 2012)