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In addition, in restoring intestinal mechanical barrier function, PNS can alleviate intestinal mucosal barrier damage by increasing the expression of ZO-1, claudin-1, and occludin in colonic mucosal tissue (Lu et al., 2020)

The interplay between inflammatory cells, mitochondrial dysfunction, and ROS production culminates in epithelial damage, a common feature portraying conditions like asthma [1316]

ROS can also influence tumor energy metabolism by regulating critical metabolic enzymes, skewing the tumor toward the pentose phosphate pathway to maintain its reducibility

10.3390/md13021037 263 SuY

Pagnussat GC, Yu HJ, Ngo QA, Rajani S, Mayalagu S, Johnson CS, Capron A, Xie LF, Ye D, Sundaresan V (2005) Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis