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Our results in mice show that if you lose even one aspect of this regulationnot the whole cell function, but just one part of its functionyou will have a compromised response to metabolic challenges. Wu believes that understanding the specific CHRNA2 signaling pathway in beige fat also opens a new avenue for identifying druggable targets to treat obesity and metabolic syndrome

doi:10.1038/s41591-020-0916-2

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