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The skin around the injection site is cleaned and sterilized, and a local anesthetic is applied to numb the area, minimizing discomfort

This work shows the first example of c-di-GMP stimulating cellular processes by mediating proteinprotein interactions

Studies suggest it may activate the Sonic Hedgehog (SHH) signaling pathway (Tayyab et al., 2019)

Given that knocking out Cpt1a in astrocytes impaired ROS generation, which physiologically maintains neuronal integrity and mouse cognition 28 , we next investigated its impact on neuronal function and behaviour